NSI-189

Cov ntaub ntawv yooj yim

 

Product Name: NSI -189

CAS Nr.: 1270138-40-3

MF: C22H30N4O

MW: 366.4998

Cov tsos thiab cov duab: Off-dawb hmoov

Hom kev siv: Nootropics

NSI-189 yog ib qho kev sim tshuaj neurogenic uas tuaj yeem kho MDD, mob hlwb raug mob, mob stroke, teeb meem kev paub, kev puas siab puas ntsws, kev nyuaj siab tom qab, thiab kab mob neurodegenerative vim kev laus.

Neuralstem Inc yog lub tuam txhab biopharmaceutical uas tsim NSI-189. Cov tshuaj tau raug tshuaj xyuas raws li lwm cov tshuaj uas tsim los rau cov neeg mob uas tsis teb rau cov tshuaj ib txwm siv.

Hauv xyoo 2011, 41 tus neeg ua haujlwm pab dawb tau ua tiav theem kuv qhov kev sim tshuaj. Ua raws li qhov no yog theem IB sim hauv xyoo 2012 thiab 2014, uas tau tsom mus rau kev kho cov neeg mob MDD.

Txawm li cas los xij, qhov kev sim tshuaj ntsuam xyuas theem II tsis ua tiav raws li theem I. Nws ua tsis tau raws li qhov yuav tsum tau ua rau qhov ua tau zoo ntawm qhov kawg ntawm MDD [R].

Tam sim no, NSI189 tseem tab tom sim rau lwm yam mob xws li kev txhim kho lub hlwb, mob ntshav qab zib neuropathy, mob stroke, kab mob neurodegenerative, kev nyuaj siab tom qab, thiab Angelman syndrome. Nws yog siv los kho mob hlwb raug mob.

FDA tau tso cai rau NSI -189 Orphan Drug Designation los kho tus kab mob tsawg, Angelman syndrome.

1. Txhim khu kev paub thiab kev nco tsim NSI-189 phosphate hmoov

2. Anxiolytic zog NSI-189 phosphate hmoov

3. Anti-depressive nyhuv NSI -189 phosphate hmoov

4. Kev Kho Mob Alzheimer's thiab Parkinson's Disease NSI-189 phosphate hmoov

5. Ua kom muaj kev sib koom tes NSI-189 phosphate hmoov

6. Txhim kho lub siab NSI-189 phosphate hmoov

7. Pab tiv thaiv qaug zog NSI-189 phosphate hmoov

8. Tiv thaiv oxidation nyob rau hauv lub hlwb NSI -189 phosphate hmoov

9. Kho cawv cuam tshuam rau lub hlwb puas NSI-189 phosphate hmoov.

Ua haujlwm zoo heev li ib qho tshuaj tiv thaiv kev nyuaj siab

Nws muaj txiaj ntsig zoo

Txhim kho kev nco thiab kev kawm

Stimulates neurogenesis (kev loj hlob ntawm cov hlwb tshiab)

NSI -189 phosphate hmoov yog cov tshuaj nootropic thiab neurogenic tshawb fawb tau los ntawm nicotinamide thiab pyrazine . NSI-189 hmoov tau pom tias yuav txhawb nqa cov neurogenesis ntawm tib neeg hippocampus-derived neural qia hlwb hauv vitro thiab hauv vivo. Lub hippocampus yog lub luag haujlwm rau kev sib sau ua ke ntawm cov ntaub ntawv los ntawm lub sijhawm luv luv mus rau lub sijhawm ntev nco, nrog rau spatial navigation. nootropics neurogenic tshuaj nsi-189 hmoov.

Vim tias qhov tseeb tias NSI -189 phosphate hmoov tseem yog ib qho tshuaj sim, tseem tsis tau muaj kev noj tshuaj tas li. Txawm li cas los xij, thaum lub sijhawm sim cov neeg mob tau txais koob tshuaj txhua hnub ntawm 40mg, 80mg, thiab 120mg ntawm qhov koob tshuaj ntau tshaj ib hnub nyob rau ntawm 28 hnub. Nyob rau lub sijhawm no, cov neeg mob tsis tau tshaj tawm cov xwm txheej loj lossis cov kev mob tshwm sim, thiab NSI -189 phosphate tau pom tias ua tau zoo. Tsis tas li ntawd, muaj qhov txo qis hauv kev nyuaj siab thiab kev paub txog cov tsos mob rau cov neeg mob noj cov tshuaj qis ntawm 40mg thiab 80mg, tab sis tsis yog rau cov neeg noj 120mg ib hnub. Qhov kev tshawb pom ua ntej ntawm qhov kev sim siab yog txhawb nqa lub tswv yim tias NSI -189 phosphate tuaj yeem kho MDD. Txawm li cas los xij, kev tshawb fawb ntxiv ntawm qhov ntau npaum li cas thiab cov txheej txheem ntawm kev ua ntawm NSI -189 phosphate yog qhov tseem ceeb los pab kom paub meej cov kev soj ntsuam ua ntej thiab pab txiav txim siab.

Sunifiram ua haujlwm zoo ib yam li qee qhov ntawm lwm cov racetams, thiab thaum sib txawv hauv cov teebmeem vim qhov chaw receptor ntxiv, ntau qhov teebmeem yog tib yam-tsuas yog exaggerated heev. Sunifiram, vim tias nws cov txheej txheem ntawm kev ua ntawm Glutamate thiab AMPA receptor sites, muaj cov txiaj ntsig tseem ceeb ntawm kev nce qib ntawm lub zog. Koj yuav hnov ​​​​zoo siab, nyob rau hauv cheeb tsam thiab npaj mus-hmoov, txawm li cas los xij, cov khawv koob yog luv luv, thiab tom qab rov sim dua ntawm cov tshuaj, txawm tias qhov kev ua siab ntev yuav tsis coj rov qab nws ib zaug ua khawv koob zoo. Txhawm rau khaws nws cov txiaj ntsig zoo tshaj plaws thawj zaug, xyuas kom koj khaws cov tshuaj kom tsawg li koj tuaj yeem ua tau, noj choline qhov chaw, thiab siv nws lub luag haujlwm (xws li: nco ntsoov noj thiab tsaug zog, tsis haus cawv, thiab ua kom lub neej noj qab haus huv.)

Sunifiram yog ib qho tshuaj txaus txaus thaum noj cov tshuaj kom tsim nyog. Sim ua kom siab ntev rau qhov tsawg kawg nkaus, thiab koj yuav ua tau zoo ntawm koj txoj hauv kev kom paub txog kev vam meej nrog Sunifiram ntseeg los ntawm koj sab!

Kev mob tshwm sim ntawm NSI-189 phosphate hmoov (1270138-41-4):

Cov kev mob tshwm sim tau tshaj tawm yog qhov ncauj qhuav, palpitations, mob taub hau, kiv taub hau, tsaug zog, qaug zog, nyob tsis tswm, pw tsaug zog tsis zoo, npau suav phem / npau suav phem, parathesia, insomnia, hyperthermia, xeev siab, mob ntawm daim tawv nqaij, thiab pob khaus.

Cim npe nrov: nsi-189, Tuam Tshoj nsi-189 lwm tus