Nicotinamide Mononucleotide

Nicotinamide Mononucleotide Cov Ntaub Ntawv Tseem Ceeb

 

Khoom npe: -Nicotinamide Mononucleotide

CAS: 1094-61-7

MF: C11H15N2O8P

PIB: 334.22

EINECS: 214-136-5

 

-Nicotinamide Mononucleotide Cov Khoom Siv Tshuaj

 

Melting point: 166 degree (lub kaum hli ntuj)

cia kub: -20 degree

Solubility: DMSO (me ntsis, rhaub), Methanol (me ntsis), dej (me ntsis)

Cov tsos mob: Dawb rau daj hmoov hmoov

Muab tso yooj yim, NMN yog ib qho tshwm sim ntawm cov molecule uas pab txhawb koj lub cev.

NMN yog ib hom molecule hu ua nucleotide. Nucleotides ua si ntau lub luag haujlwm hauv koj lub cev, suav nrog ua lub tsev thaiv DNA.

Hauv koj lub hlwb, NMN hloov mus rau lwm lub molecule hu ua nicotinamide adenine dinucleotide (NAD). Koj lub cev xav tau NAD rau ntau yam haujlwm koom nrog hauv cov metabolism thiab lub zog tsim khoom.

Tej zaum koj yuav xav txog NMN raws li cov khoom siv raw thiab NAD raws li cov qauv kho kom zoo uas koj lub cev tuaj yeem siv tau.

Tus nqi ntawm NAD koj lub cev tuaj yeem ua tau nyob ntawm tus nqi NMN muaj nyob hauv koj lub cev.

Txhua lub hlwb hauv koj lub cev siv NAD thiab yog li xav tau NMN, nws cov thawj coj, ua haujlwm kom zoo. NAD pab cov hlwb tswj ntau lub luag haujlwm tseem ceeb uas pab ua kom koj lub hlwb ua haujlwm zoo, suav nrog:

• Lub zog metabolism
• kho DNA
• Gene qhia
• Cellular stress teb

Nws yog ib qho tseem ceeb uas koj lub hlwb muaj ntau NMN los tsim NAD txaus los txhawb cov haujlwm no.

Koj cov qib NMN ib txwm poob qis dhau sijhawm, thiab, vim li ntawd, koj qib NAD poob, ib yam nkaus. Qhov no yuav ua rau muaj qee yam teebmeem kev noj qab haus huv uas koj tuaj yeem ntsib thaum laus.

Piv txwv li, kev tshawb fawb tau pom tias cov neeg muaj hnub nyoog sib txawv, suav nrog ntshav qab zib thiab kab mob siab, tuaj yeem muaj qib qis ntawm NMN thiab NAD.

Test-tube thiab tsiaj tshawb fawb kuj qhia tias NMN tuaj yeem ua lub luag haujlwm hauv lwm yam ntawm kev laus, suav nrog lub plawv thiab lub hlwb.

Yog tias koj tau hnov ​​​​NMN, koj kuj yuav tau hnov ​​​​txog nicotinamide riboside (NR). NR yog lwm cov molecule zoo ib yam li NMN uas tib neeg kuj siv los ntxiv rau kev laus noj qab haus huv.

Cov pov thawj qhia tias lub cev hloov NR rau hauv NMN, uas tom qab ntawd hloov mus rau NAD.

Txij li thaum noj NMN tuaj yeem pab koj lub cev tsim NAD ntau dua, nws tseem ceeb heev kom xav txog kev tshawb fawb tom qab cov txiaj ntsig ntawm NAD. Cov kev tshawb fawb tshawb xyuas NAD tau teeb pom kev ntawm nws cov txiaj ntsig zoo:

• Nws yuav ua rau kom lub neej ntev. Hauv koj lub hlwb, NAD qhib ib pab pawg proteins hu ua sirtuins, uas pab kho koj cov DNA. Cov dej num ntawm sirtuins yog txuas mus rau lub neej ntev. Ntawm qhov ntxeev sab, qib qis-NAD yog txuam nrog cov kab mob muaj hnub nyoog.
• Tej zaum nws yuav muaj kev tiv thaiv ntawm lub hlwb. NAD tau xav tias yuav hloov kho cov protein ntau uas pab tiv thaiv cov hlwb tiv thaiv kev puas tsuaj ntawm mitochondrial kev ua haujlwm thiab oxidative kev nyuaj siab. Cov cellular stressors muaj feem xyuam rau qee cov kab mob neurological, suav nrog Alzheimer's disease.
• Nws tuaj yeem pab txo cov kab mob plawv. ResearchTrusted Source nyob rau hauv nas tau pom tias siab NAD qib hauv cov ntshav thim rov qab hnub nyoog txog kev puas tsuaj rau cov hlab ntsha, uas tuaj yeem pab tiv thaiv kab mob plawv.
• Nws tuaj yeem tiv thaiv kab mob qog noj ntshav. Kev nce qib NAD tuaj yeem pab tiv thaiv cov hlwb tiv thaiv oxidative kev nyuaj siab thiab DNA puas tsuaj, uas cuam tshuam nrog kev txhim kho qog noj ntshav.
• Nws tuaj yeem pab nrog jet lag. ResearchTrusted Source qhia tias NAD tuaj yeem pab kho koj lub moos sab hauv, muaj peev xwm pab tau yooj yim lub dav hlau lag lossis lwm yam kab mob circadian atherosclerosis.
• Nws tuaj yeem pab cov leeg laus. StudiesTrusted Source hauv cov nas laus tau pom tias cov ntshav siab NAD tau pab txhim kho cov leeg nqaij, lub zog, thiab kev ua siab ntev ntawm cov nas laus.
• Nws yog ib qho tseem ceeb kom nco ntsoov tias cov txiaj ntsig no tau pom rau NAD, tsis yog rau NMN tshwj xeeb. Kev tshawb fawb ntxiv txog cov txiaj ntsig ntawm NMN thiab NAD yog xav tau.

Muab cov ntaub ntawv txwv tsis pub muaj nyob rau ntawm kev noj NMN tshuaj, nws nyuaj rau txiav txim siab qhov koob tshuaj zoo tagnrho. Cov kev tshawb fawb tau pom cov txiaj ntsig kev noj qab haus huv nrog cov koob tshuaj tsawg li 250 mg ntawm NMN ib hnub, txog li 1,200 mg txhua hnub.

Tsuas yog peb txoj kev tshawb fawb, suav nrog cov uas tau piav qhia saum toj no, tau saib cov txiaj ntsig ntawm kev noj NMN tshuaj ntxiv ntau npaum li cas. Qhov tseem ceeb, kev nyab xeeb tsis tshwm sim txawv ntawm cov koob tshuaj sib txawv ntawm NMN siv.

Hauv qhov kev tshawb fawb Trusted Source uas muaj cov neeg ua haujlwm ua haujlwm, cov txiaj ntsig aerobic ntawm NMN supplementation tau ntau dua nrog ntau dua ntawm NMN (1,200 mg) piv nrog qis dua (300 mg). Tab sis tsis muaj qhov sib txawv tau pom nyob rau hauv cov txiaj ntsig tau pom ntawm koob tshuaj siab piv nrog cov koob tshuaj nruab nrab (600 mg).

Cim npe nrov: Tuam Tshoj nicotinamide mononucleotide lwm tus neeg