Exemestane hmoov

Exemestane hmoov

Khoom npe: exemestane, aromasin hmoov
CAS: 107868-30-4
Molecular Cov Qauv: C20H2O2
Molecular hnyav: 296.4
Purity: 99%
Zog: Cov hmoov dawb dawb
Lub cev daim ntawv: khoom
Melting taw tes: 155.13Aac
Cia Temp: Chav Chav Dej
Ib nrab lub neej: 24 teev
Feem ntau cov tshuaj: 12.5mg ib hnub
Nrhiav kom tau sijhawm: 2 lub lis piam
Chav Kawm Siv Tshuaj: Anti-Estrogen

Phim tshaj plaws hmoov qhia:

Exemestane, cov npe npe {{}} methyleneandosta}} dione {}}} dione}, {}}}}} dione}, {}} Nws tau pom zoo thawj zaug kev lag luam hauv UK nyob rau lub Plaub Hlis 1999, thiab tau tsim tawm hauv Tebchaws Meskas, Tebchaws Yelemees, Switzerland, Canada thiab Nordic lub tebchaws. Nws yog tsuas yog siv nyob rau hauv kev kho mob cancer mis mob hauv cov poj niam postmenopausal. Nws cov kev ua tshuab ntawm kev ua yog irreversible khi rau lub tsev kawm ntawv txheej txheem ntawm cov duab aromatase thiab li no txo ​​qib aromatic thiab li no txo ​​cov tshuaj estrogen hauv ntshav. Exemestane muaj qhov muaj zog thiab tshwj xeeb aromatase nyhuv. Raws li ib txoj kab thib ob thiab cov poj niam thib peb rau cov poj niam estrinage, nws yog qhov ua rau mob qog nqaij hlav, nrog ob peb cov kev tsis sib haum xeeb, uas qhia tau zoo thov kev cia siab.

Kev loj hlob ntawm cov kabmob kheesxaws ntawm cov tshuaj mob kheesxaws muaj peev xwm vam khom ntawm cov tshuaj estrogen. Cov tshuaj estrogen (estrone thiab estradiol) nyob rau hauv cov poj niam postmenopausal yog tsuas yog hloov pauv ntawm Androgen (androgenenione thiab testosterone) nyob rau hauv cov qog adrenal thiab ovaries. Tiv thaiv kev tsim hluav taws xob ntau lawm los ntawm kev tiv thaiv aromatase yog kev xaiv tshuaj rau postmenopausal tshuaj mob cancer. Exemestane yog ib qho tsis muaj zog steroid aromatase inactivator. Nws yog kev tsim qauv zoo li androstenione, lub ntuj substrate ntawm enzyme, thiab yog pseudo-substrate ntawm aromatase. Nws tuaj yeem ua tsis tau tus enzyme los ntawm irreveribly khi rau nws cov neeg nquag, tab sis tsis muaj qhov cuam tshuam ntawm biosynthesis ntawm corticosteroids thiab aldosterone ntawm lub qog adrenal. Ntawm ib qho kev sib haum xeeb 600 lub sij hawm siab dua li cov duab aromease, nws tsis muaj qhov cuam tshuam tseem ceeb ntawm lwm cov enzymes hauv steroidogenesis txoj kev.

Kev loj hlob ntawm cov kabmob kheesxaws ntawm cov tshuaj mob kheesxaws muaj peev xwm vam khom ntawm cov tshuaj estrogen. Cov tshuaj estrogen (estrone thiab estradiol) nyob rau hauv cov kev ncig ntawm postmenopausal ntawm andrreesosterone thiab ovaries los ntawm aromatase hauv cov ntaub so ntswg peripheral. Tiv thaiv kev tsim hluav taws xob ntau lawm los ntawm kev tiv thaiv aromatase yog ib txoj kev tsim nyog thiab kev xaiv rau kev kho mob cancer offone-ependent Exemestane yog ib qho tsis muaj zog sterroidal aromatase inactivator. Nws yog qhov zoo sib xws hauv lub ntuj substrate ntawm enzyme, androstenione, thiab yog pseudo-subtstrate ntawm aromatase. Nws tuaj yeem ua tsis tau tus enzyme los ntawm irreveribly khi rau nws cov neeg nquag, tab sis tsis muaj qhov cuam tshuam ntawm biosynthesis ntawm corticosteroids thiab aldosterone ntawm lub qog adrenal. Ntawm ib qho kev pom zoo 600 lub sij hawm siab dua li cov concibits uas inhibits aromatase, nws tsis muaj qhov cuam tshuam tseem ceeb ntawm lwm cov enzymes hauv steroidogenesis txoj kev.

Exemestane yog ib tug aromatase inhibitor qhia rau:

Kev Kho Mob Ntxiv ntawm cov poj niam EsTmenopausal nrog Estrogen-receptor zoo thaum ntxov thaum muaj peb xyoos dhau los ua tiav ntawm kev kho mob hormones kom ua tiav.

Cov tshuaj no siv kho qee yam mob cancer mis (xws li cov tshuaj hormones mis (xws li tus mob cancer mis) hauv cov poj niam tom qab lawm. Exemestane tseem siv los pab tiv thaiv tus mob qog los ntawm rov qab los. Qee cov qog mis mis yog qhov tsim kom loj hlob sai dua los ntawm lub tshuaj hormones zoo hu ua estrogen. Exementane txo tus nqi ntawm cov tshuaj estrogen lub cev ua thiab pab qeeb lossis rov qab ua kom muaj kev loj hlob ntawm cov kua mis mis no.

Pom zoo cov koob tshuaj: ib qho 25 mg ntsiav tshuaj ib zaug txhua hnub tom qab noj mov.

Cim npe nrov: Kws Zoo Nkauj Hmoov, Tuam Tshoj Exemestane Hmoov Tuam Tshoj, cov chaw muag khoom, Hoobkas