Fareston Basic Information

Fareston (tshwj xeeb lub npe: toremifene) yog ib qho tshuaj estrogen receptor modulator (SERM) siv los kho cov tshuaj metastatic hormone receptor-zoo mob qog noj ntshav mis hauv cov poj niam postmenopausal.

Khoom npe: Fareston

Synonyms: TOREMIFENE; Toremifene citrate

CAS: 89778-27-8

MF: C32H36ClNO8

MW: 598.08

EINECS: 663-344-6

Yam khoom: SERMs

Mol File: 89778-27-8.mol

product-216-201

Toremifene citrate Chemical Properties

Melting point: 160-162 degree

Boiling point: 146-148C

Qhov ceev: 1,045g / cm3

Refractive index: 1,{1}},418

Cia kub: 2-8 degree

Solubility: DMSO: >10 mg/ml

Daim ntawv: hmoov

PIB: 14,9550

Stability: Lub teeb Sensitive

Xim: dawb mus rau dawb hmoov

Fareston ua haujlwm li cas?

Fareston thaiv cov teebmeem ntawm estrogen ntawm metastatic hormone receptor-zoo mob qog noj ntshav mis los ntawm zaum hauv cov tshuaj estrogen receptors ntawm cov hlwb. Yog hais tias Fareston nyob rau hauv lub receptor, estrogen tsis tuaj yeem txuas mus rau cov qog nqaij hlav cancer thiab lub cell tsis tau txais cov tshuaj estrogen cov cim kom loj hlob thiab ntau ntxiv.

Fareston yuav tsis ua haujlwm ntawm cov tshuaj hormone receptor-tsis zoo mob cancer mis.

Fareston puas yog rau koj?

Yog tias koj yog ib tus poj niam postmenopausal kuaj mob metastatic hormone receptor-zoo mob qog noj ntshav mis, Fareston yuav yog ib qho kev kho mob zoo rau koj.

Koj yuav tsum tsis txhob noj Fareston yog tias koj muaj:

Mob plawv dhia hu ua long QT syndrome
Txo cov ntshav cov poov tshuaj
Tsawg cov ntshav magnesium
Keeb kwm ntawm cov ntshav txhaws
Endometrial hyperplasia, ib qho overgrowth ntawm cov hlwb nyob rau hauv ob sab phlu ntawm lub tsev menyuam

Koj yuav tsum tsis txhob noj Fareston yog tias koj pub niam mis, cev xeeb tub, sim cev xeeb tub, lossis yog tias muaj lub sijhawm uas koj tuaj yeem xeeb menyuam. Fareston tuaj yeem ua rau muaj kev puas tsuaj rau cov embryos. Koj yuav tsum siv hom tshuaj tiv thaiv kev yug menyuam tsis zoo thaum koj noj Fareston. Nug koj tus kws kho mob seb hom kev tiv thaiv kev yug menyuam uas tsis yog tshuaj hormones yuav zoo tshaj rau koj.

Fareston cov kev mob tshwm sim

Zoo li yuav luag txhua yam tshuaj mob qog noj ntshav mis, Fareston tuaj yeem ua rau muaj kev phiv, qee yam mob hnyav.

Cov kev mob tshwm sim feem ntau ntawm Fareston yog:

Kub flashes
hws
Ntshai
Qhov chaw mos tawm

Fareston kuj tseem tuaj yeem ua rau muaj kev phiv loj heev, suav nrog:

QT ncua ntev, uas tuaj yeem ua rau muaj kev hloov pauv hauv koj lub plawv dhia. Qhia rau koj tus kws kho mob tam sim yog tias koj muaj:

Ua tsis taus pa
mob hauv siab
kiv taub hau lossis qaug zog
Fluttering los yog palpitations ntawm lub plawv
Lightheadedness uas los thiab mus
qaug dab peg

Q&A

Q: Qhov txawv ntawm tamoxifen thiab toremifene yog dab tsi?

A: Cov txheej txheem: Toremifene yog cov qauv zoo ib yam li tamoxifen, txawv ntawm ib qho tshuaj chlorine nkaus xwb, thiab muaj cov tshuaj pharmacological zoo sib xws. Qhov sib txawv loj ntawm ob lub tebchaw yog nyob rau hauv kev ua haujlwm preclinical; mob ntev, koob tshuaj tamoxifen yog hepatocarcinogenic nyob rau hauv nas, qhov toremifene tsis yog.

Q: Dab tsi thaiv cov tshuaj estrogen ua rau koj lub cev?

A: SERMs yog cov tshuaj antiestrogen uas khi rau cov tshuaj estrogen receptor. Qhov no txwv cov tshuaj estrogen los ntawm kev khi rau cov receptor thiab txhawb kev loj hlob ntawm cov qog nqaij hlav cancer. SERMs suav nrog tamoxifen, toremifene, thiab raloxifene. Lawv raug coj los ua tshuaj.

Q: Puas yog toremifene yog hom tshuaj khomob?

A: Fareston (toremifene citrate) yog ib qho tshuaj estrogen agonist / antagonist uas thaiv cov tshuaj estrogen kom tsis txhob ncav cuag cov qog nqaij hlav cancer siv los ua kom qeeb ntawm kev loj hlob ntawm cov qog nqaij hlav cancer mis (mob qog noj ntshav uas tau kis los ntawm cov qog qub). Tsis zoo li kws khomob, Fareston tsis ua kom cov qog nqaij hlav cancer.

Q: Puas muaj lwm txoj kev nyab xeeb rau tamoxifen?

A: Toremifene yog ib qho txiaj ntsig zoo thiab muaj kev nyab xeeb rau tamoxifen hauv kev kho mob endocrine rau kev mob qog noj ntshav mis: cov txiaj ntsig ntawm plaub qhov kev sim randomized. Kev kho mob cancer mis.

Cim npe nrov: Fareston, Tuam Tshoj Fareston lwm tus neeg