Procaine Base

Product details

 

Khoom npe: Procaine Base

CAS Nr.: 59-46-1

Cov mis mos molecular: C13H20N2O1

Molecular Luj: 236.31

EINECS tus lej: 200-426-9

Melting point: 61C (Tshaj tawm)

Cia txias: Chav kub lossis 2-8C

Purity: >99%

Standard: Pharmaceutical Qib

Cov tsos mob: Dawb los yog yuav luag dawb crystal hmoov

Procaine Base yog ib qho tshuaj loog uas qhia rau kev tsim tshuaj loog hauv zos lossis cheeb tsam, tshwj xeeb tshaj yog rau kev phais qhov ncauj. Procaine muaj qhov zoo ntawm kev txwv cov hlab ntsha uas txo cov ntshav, tsis zoo li lwm cov tshuaj loog hauv zos xws li lidocaine. Procaine yog ib qho tshuaj loog ester. Nws yog metabolized nyob rau hauv lub plasma los ntawm enzyme pseudocholinesterase los ntawm hydrolysis mus rau hauv para-aminobenzoic acid, uas yog ces tawm los ntawm ob lub raum mus rau hauv cov zis.

Procaine feem ntau yog siv rau infiltration anesthesia, peripheral paj hlwb, thiab txha caj qaum.

Procaine yog siv los txhaj tshuaj thaum phais thiab lwm yam kev kho mob thiab kho hniav.

Procaine tau pom zoo rau kev siv rov qab kev laus hauv lub sijhawm niaj hnub no, nws tuaj yeem siv los tiv thaiv kev mob caj dab, arteriosclerosis, senile ntawm daim tawv nqaij hloov thiab baldness. Procaine uas muaj benzoic acid tau pom zoo kom txhim kho qhov nqus ntawm procaine los ntawm cov rog, yog li ua kom nws nqus tau los ntawm tib neeg lub cev.

Procaine kuj nce qhov ceev uas cov hlab ntsha ua impulses, thiab txo tus nqi ntawm excretion ntawm 17 kerosteroids, uas feem ntau nce nrog lub hnub nyoog.

Cov txiaj ntsig los tiv thaiv kev laus ntawm Procaine Base suav nrog kev nce paj hlwb, txhim kho kev noj qab haus huv thiab muaj peev xwm ua neej nyob ntev.

Procaine-Base-Infusion (Procaine HCl / Procaine Base):

Tus tswv lub npe: Novocain

Classification: Local tshuaj loog

Muaj peev xwm: 1% (10 mg / ml)

Qhov nruab nrab rov qab koob tshuaj (IV): 1-5 ml

Ib koob tshuaj ntau tshaj: 1-5 ml

Tag nrho cov koob tshuaj ntau tshaj: 5 ml

Procaine yog ib qho tshuaj loog hauv zos ntawm pawg amino ester, uas ua los ntawm ntau lub hom phiaj.Target: OthersProcaine yog ib qho tshuaj loog hauv zos ntawm hom ester uas muaj qhov pib qeeb thiab lub sijhawm luv luv ntawm kev ua.Procaine (0.01 -100 microM) inhibited lub 5-HT3 receptor-mediated sab hauv tam sim no nyob rau hauv tag nrho-cell patch clamp kaw. Procaine zoo li tsim kev sib tw inhibition ntawm 5-HT3 receptors nrog KD ntawm 1.7 microM

Procaine yog DNA-demethylating tus neeg sawv cev uas ua rau txo qis 40% hauv 5-methylcytosine DNA cov ntsiab lus raws li kev txiav txim siab los ntawm kev ua haujlwm siab capillary electrophoresis lossis tag nrho DNA enzyme digestion. Procaine tseem tuaj yeem demethylate densely hypermethylated CpG Islands tuaj. Procaine kuj muaj kev loj hlob-inhibitory cuam tshuam nyob rau hauv cov qog nqaij hlav cancer, ua rau mitotic ntes

Procaine ua haujlwm raws li qhov ua kom muaj zog ntawm limbic system hlwb, thiab qhov ntawd procaine hloov pauv kev sib kis ntawm synaptic hauv qee qhov, tab sis tsis yog tag nrho, tso tawm txoj hauv kev los ntawm amygdale.

Cim npe nrov: Procaine Base, Tuam Tshoj Procaine Base lwm tus neeg