Minoxidil

Cov ntaub ntawv yooj yim

 

Khoom npe: Minoxidil

Qhov tsos: Dawb hmoov

CAS: 38304-91-5

Purity: 99%

MF: C9H15N5O

Muaj nuj nqi: Los tiv thaiv plaub hau

Minoxidil yog thawj cov tshuaj pom zoo los ntawm FDA rau kev kho mob ntawm androgenetic alopecia (cov plaub hau poob). Ua ntej ntawd, minoxidil tau siv los ua cov tshuaj vasodilator uas tau muab los ntawm cov ntsiav tshuaj hauv qhov ncauj los kho cov ntshav siab, nrog rau cov kev mob tshwm sim uas suav nrog kev loj hlob ntawm cov plaub hau thiab thim rov qab ntawm txiv neej baldness. Hauv xyoo 1980, UpJohn Corporation tau tawm los nrog cov tshuaj pleev ib ce ntawm 2% minoxidil, hu ua Rogaine, rau kev kho mob tshwj xeeb ntawm androgenetic alopecia. Txij li thaum xyoo 1990, ntau hom tshuaj minoxidil tau dhau los ua kev kho plaub hau thaum lub qhov ncauj tseem siv los kho cov ntshav siab.

Minoxidil yog cov tshuaj vasodilator uas paub txog nws lub peev xwm los ua kom cov plaub hau tsis muaj zog thiab txhawb cov plaub hau regrowth. Nws muaj nyob rau ntawm lub txee rau kev kho mob ntawm androgenic alopecia, ntawm lwm yam kev kho mob baldness, tab sis ntsuas kev hloov pauv ploj hauv lub hlis tom qab txiav kev kho mob. Nws txoj kev ua tau zoo tau tshwm sim nyob rau hauv cov txiv neej hluas (18 txog 41 xyoo), tus hluas qhov zoo dua, thiab hauv cov neeg uas muaj balding nyob rau hauv nruab nrab (vertex) feem ntawm cov tawv taub hau.

• Minoxidil tuaj yeem txhawb kev loj hlob thiab kev sib txawv ntawm cov plaub hau follicle epithelial hlwb: tib neeg cov plaub hau follicle epithelial hlwb hauv ntau qhov sib txawv ntawm cov tshuaj minoxidil hauv micro-molar concentration ntawm minoxidil tuaj yeem txhawb cov plaub hau follicle epithelial cell proliferation.
• Minoxidil tuaj yeem txhawb nqa angiogenesis: nce cov ntshav hauv zos: cov plaub hau kev loj hlob nyob ntawm cov plaub hau txiv mis ntshav cov khoom noj khoom haus, cov plaub hau nyob rau hauv lub voj voog loj hlob sib txawv, vascular endothelial kev loj hlob mRNA qhia txawv ntawm kev loj hlob ntawm vascular endothelial kev loj hlob mRNA nyob rau hauv lub dermis lub txiv mis. tau hais tawm tau zoo heev, tab sis tau hais tsawg dua thaum lub sijhawm rov qab los thiab so.
• Minoxidil tuaj yeem qhib cov kab poov tshuaj: potassium channel qhib yog ib kauj ruam tseem ceeb hauv kev tswj cov plaub hau kev loj hlob, tsiaj cov qauv hauv vitro thiab hauv vivo thwmsim tau pom tias minoxidil yog cov poov tshuaj channel activator, tuaj yeem nce permeability ntawm cov poov tshuaj ions los tiv thaiv calcium ion flow Intracellular, ua rau txo cov calcium dawb hauv cov hlwb, thaum calcium ions, epidermal kev loj hlob inhibit cov plaub hau kev loj hlob.

Nws tuaj yeem siv rau refractory hypertension thiab lub raum kub siab, cov teebmeem antihypertensive ntawm hydralazine muaj zog dua li ntawd. Mechanism rau K + channel qhib, kom vascular du leeg. Nws yog cov chav kawm vasodilator antihypertensive tshuaj. Tsis ua rau orthostatic hypotension, tsis muaj kev siv tshuaj ntev ntev.

Minoxidil yog thawj cov tshuaj pom zoo los ntawm FDA rau kev kho mob ntawm androgenetic alopecia (cov plaub hau poob). Ua ntej ntawd, minoxidil tau siv los ua cov tshuaj vasodilator uas tau muab los ua cov ntsiav tshuaj hauv qhov ncauj los kho cov ntshav siab uas suav nrog cov plaub hau loj hlob thiab thim rov qab ntawm txiv neej baldness.

Minoxidil ncaj qha dilates cov hlab ntsha me thiab yog li ua rau cov ntshav siab, tab sis qhov tseeb mechanism tsis meej. Cov khoom no tsis dilate venules. Kev txo qis peripheral vascular tsis kam ua rau muaj zog ntxiv lub plawv dhia thiab lub plawv tso zis. Kev ua haujlwm ntawm Renin nce ntxiv tom qab hypotension, ua rau dej thiab sodium tuav. Cov khoom no tsis cuam tshuam nrog cov hlab ntsha lub cev muaj zog Chemicalbook reflex, yog li tsis muaj orthostatic hypotension. Minoxidil yog ib qho tshuaj uas siv tau thiab zoo rau kev kho mob ntawm alopecia, tab sis nws cov tshuaj siv tshuaj thiab nws lub hom phiaj ntawm lub hlwb tsis meej heev, cov kev tshawb fawb tsis ntev los no tau pom tias minoxidil tuaj yeem txhawb cov plaub hau kev loj hlob los ntawm cov hauv qab no.

Tshuaj pleev minoxidil yog hom tshuaj feem ntau siv rau cov plaub hau regrowth. Cov lus qhia ntawm daim ntawv thov thiab zaus yuav nyob ntawm qhov tsim, tab sis ntawm no yog cov lus qhia ib kauj ruam ntawm kev siv tshuaj pleev minoxidil:

Tham nrog tus kws kho mob tshwj xeeb
Ua ntej pib tshuaj pleev minoxidil, sab laj nrog kws kho mob dermatologist lossis kws kho mob los ntsuas koj cov plaub hau tsis zoo thiab tau txais kev taw qhia tus kheej.

Xaiv Txoj Cai Txoj Cai
Tshuaj pleev minoxidil los ntawm ntau lub zog, xws li 2% thiab 5%. Koj tus kws kho mob yuav pom zoo kom tsim nyog lub zog raws li koj cov kev xav tau tshwj xeeb.

Npaj cov tawv taub hau
Xyuas kom lub cheeb tsam daim ntawv thov huv si thiab qhuav tag. Tej zaum nws yuav muaj txiaj ntsig zoo rau lub sijhawm siv tshuaj pleev minoxidil rau tom qab da dej, kom tso sijhawm ntau npaum li qhov ua tau rau minoxidil zaum ntawm tawv taub hau thiab siv tau.

Siv cov tshuaj los yog ua npuas ncauj
Dispense tus nqi pom zoo ntawm cov tshuaj minoxidil mus rau thaj chaw lub hom phiaj. Massage nws rau ntawm daim tawv nqaij ntawm daim tawv nqaij nrog koj lub ntsis ntiv tes, kom ntseeg tau tias txawm tias qhov chaw cuam tshuam. Koj tus kws kho mob tuaj yeem muab kev qhia txog pes tsawg zaus koj yuav tsum ua qhov no txhua hnub. Nco ntsoov, minoxidil yog tawv taub hau thiab tsis yog kev kho plaub hau, yog li kev sib cuag nrog daim tawv nqaij yog qhov tseem ceeb. Tom qab ntawd, koj tuaj yeem kho koj cov plaub hau zoo li koj ib txwm ua.

Tso cai Absorption
Cia cov tshuaj minoxidil los yog ua npuas dej nyob hauv daim tawv nqaij rau ob peb teev lossis ntev li ntev tau kom tso sijhawm rau cov tshuaj nkag mus rau ntawm daim tawv nqaij thiab ncav cuag cov hauv paus plaub hau.

Kev sib haum xeeb yog qhov tseem ceeb
Txhawm rau ua tiav cov txiaj ntsig zoo tshaj plaws, siv tshuaj minoxidil tsis tu ncua raws li kev pom zoo los ntawm koj tus kws kho mob. Tej zaum nws yuav siv li ob peb lub hlis ua ntej koj pib pom kev txhim kho cov plaub hau loj hlob. Nco ntsoov tias kev tso tawm tuaj yeem tshwm sim hauv thawj lub hlis lossis tom qab pib kho. Koj tuaj yeem mus saib cov lus no ntawm minoxidil shedding kom paub ntau ntxiv txog qhov no tab sis ib ntus teb rau kev kho plaub hau.

Cim npe nrov: Tuam Tshoj minoxidil manufacturers, lwm tus neeg, Hoobkas